The Design and Implementation of Updating and Monitoring Alternative Splicing Database

Abstract

Alternative splicing is a very important mechanism of gene expression in eukaryotic cells, to understand the forms of alternative splicing expression will be helpful to the research of medical science. However, since the huge amount of genomic sequence data, it costs huge computation time to construct an alternative splicing database. Since the genome sequencing project is still on going, an alternative splicing database needs to be updated from time to time. Traditionally, researchers just reconstruct the alternative splicing database when it needs to be updated. It will take huge computation time. Hence, we use the intelligence agent technology to help us analyzing the data and decrease the updating time. After the evaluation, our agent can decrease upper to 93% updating time compared to the traditional method of alternative splicing database updating.