Web-Based DNA Sequence Annotation Tools for Functional Genomics

Abstract

In this paper, we will present the design and implement of two web-based tools for DNA sequence data annotation. Our tools integrate functional genomics sequence data from different sources and in differecnt formats. One tool handles the e-mails that contain DNA sequence data from sequencing machine and lets the user view and edit the sequences. The sequences may then be stored in a local dta warehouse or be sent to a remote database to search for matches. Another tool handles the database search results and lets the user annotate the matched seuqences before storing the data into database, called CR Base, for further exploration. Our tools use the Internet Web Browser as the only user interface, so that the user may use the tools to access CR Base and to perform data manipulation on Internet.